Preeclampsia with proteinuria
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All parturients were singleton pregnancies. Preeclampsia with proteinuria is defined as the onset of hypertension (BP >= 140/90 mmHg) and proteinuria (24-hour urine protein >= 300 mg) after 20 weeks of gestation, in the absence of prior hypertension. Severe preeclampsia is diagnosed with higher blood pressure readings (systolic BP >= 160 mmHg and/or diastolic BP >= 110 mmHg), more severe proteinuria (24-hour urine protein >= 2 g), signs of preeclamptic convulsions or eclampsia, HELLP syndrome, or acute pulmonary edema.
Exclusion criteria
Exclusion criteria: Exclusion criteria encompass a history of preeclampsia, premature rupture of membranes, illicit drug use, and chronic conditions such as diabetes, chronic hypertension, infections, and renal diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pyroptosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Serum creatinine;Gestational age;soluble Fms - like tyrosine kinase - 1;fetal Apage score;Kidney injury molecule - 1;perinatal adverse events;Blood urea nitrogen;Placental growth factor;fetal weight;proteinuria;Neutrophil gelatinase - associated lipocalin; | — |
Countries
China
Contacts
Tianjin Central Hospital of Gynecology Obstetrics