postoperative delirium
Conditions
Interventions
oliceridine:oliceridine:Dilute at a dose of 0.4 mg/kg with normal saline to 100 ml. Set the background infusion rate to 2 ml/h, the single compression dose to 2 ml, the lock time to 15 minutes, and t
O+TAPB:Dilute at a dose of 0.4 mg/kg with normal saline to 100 ml. Set the background infusion rate to 2 ml/h, the single compression dose to 2 ml, the lock time to 15 minutes, and the maximum dose p
TAPB:Ultrasound-guided bilateral transversus abdominis plane block: 20ml of 0.2% ropivacaine on one side, totaling 40 ml.
Sponsors
People's Hospital of Liupanshui City
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age>=60 years old; 2. Elective major abdominal surgery, the estimated operation time is >=2h; 3. ASAI.-III. 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Previous history of schizophrenia, epilepsy, or Parkinson's disease; 2. Severe dementia, language impairment, or terminal disease that cannot complete the preoperative evaluation; 3. The score of the Mini-Mental State Examination Scale (MMSE) before surgery is too low (illiteracy score <=17 points, total score of primary school level <=20, total score of secondary school or above <=22); 4. Those who have a positive Allen test, infection at the arterial puncture site, hypercoagulability, etc., cannot undergo arterial puncture; 5. Other situations that the investigator believes are not suitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence of delirium within 5 days after the operation; | — |
Countries
China
Contacts
Public ContactDing Jifei
People's Hospital of Liupanshui City
Outcome results
None listed