Autism Spectrum Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children who are over 18 months old but under 24 months old, whose first language is Mandarin, and whose parents are willing to cooperate with the assessment and follow-up and have the ability to independently fill out questionnaires, are willing to undergo follow-up assessments at 24 months old, 30 months old, and 36 months old after their children are included in the study. For the ASD group, it is necessary to meet the DSM-5 diagnostic criteria for autism spectrum disorder, have significant social communication deficits and repetitive stereotyped behavior patterns, and the Autism Observational Diagnostic Scale indicates mild risk or above. For the TD group, it is necessary to have normal growth and development status, no obvious defects in social skills development, repetitive stereotyped behavior patterns, signs of delayed motor development or language development, and no previous diagnosis or suspicion of neurodevelopmental disorders.
Exclusion criteria
Exclusion criteria: 1. Diagnosed with syndromic autism such as Rett syndrome and fragile X syndrome; 2. Neurological disorders that affect the growth, development, or cognition of participants, such as central nervous system infections, epilepsy, etc; 3. Congenital heart disease, congenital metabolic disease; 4. Visual or hearing impairments, sensory impairments, or physical disabilities; 5. There is a clear perinatal cranial injury or disease, such as severe asphyxia, hypoxic encephalopathy, intracranial hemorrhage; or it may cause perinatal brain injury due to exposure to exogenous compounds such as alcohol and certain prescription drugs in the uterus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inhibitory Ability;EEG;Social Attention Capacity; | — |
Countries
China
Contacts
The Third Affiliated Hospital Sun Yat-sen University