Postoperative pulmonary complications
Conditions
Interventions
Lung manual recruitment group:Lung manual recruitment(Set the ventilator to manual mode, adjust the APL valve to 30 cmH2O, and after the anesthesia machine's reservoir bag is inflated, squeeze the res
Simple lung protective ventilation group:Lung protective ventilation(The tidal volume is set at 6 ml/kg of the ideal body weight, with an inspiratory-to-expiratory ratio of 1:2. The inspiratory pause
Sponsors
Fuzhou University Affiliated Provincial Hospital
Eligibility
Sex/Gender
All
Age
8 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age>=8 years old, <=80 years old. 2. Patients who underwent elective minimally invasive cardiopulmonary bypass cardiac surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with emergency surgery. 2. Previous thoracotomy heart surgery. 3. Preoperative diagnosis of lung infection. 4. Severe pulmonary dysfunction and acute respiratory distress syndrome (ARDS) before surgery. 5. Severe liver and kidney insufficiency before surgery. 6. Received mechanical ventilation within 2 months before surgery. 7. Preoperative pulmonary function indicators meet one or more of the following: I) FEV1 (forced expiratory volume in the first second) 50 mmHg 8. Acute heart failure within 2 months before surgery. 9. Participated in other similar trials in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary function indicators;Postoperative 24-hour oxygenation index (PaO2/FiO2).;Arterial blood gas analysis indicators (PaO2, PaCO2, pH value, etc.).;Lung compliance.;Duration of mechanical ventilation.;Length of stay in the ICU.;Postoperative levels of inflammatory markers (such as IL-6, TNF-a, etc.).; | — |
Countries
China
Contacts
Public ContactShuangbo Dai
Fuzhou University Affiliated Provincial Hospital
Outcome results
None listed