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Multi-Modality Imaging Biomarkers in Evaluating Obesity-Associated Comorbidity Changes at Pre- and Post-Bariatric Surgery in an Obese Population: A Prospective and Longitudinal Cohort Study

Multi-Modality Imaging Biomarkers in Evaluating Obesity-Associated Comorbidity Changes at Pre- and Post-Bariatric Surgery in an Obese Population: A Prospective and Longitudinal Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108542
Enrollment
Unknown
Registered
2025-09-01
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Control:None

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Obesity Cohort — Prospective inclusion of obese patients undergoing weight-loss surgery at the Department of Bariatric Surgery, Qilu Hospital, Shandong University, from June 2025 to June 2028. Inclusion criteria: 1) Obesity patients (BMI >= 27.5 kg/m² with obesity-related comorbidities, or BMI >= 32.5 kg/m²); 2) Age >= 18 years; 3) No claustrophobia, no metallic implants (e.g., pacemakers, metal plates, etc.); 4) No severe organ dysfunction of the heart, lungs, liver, kidneys, etc. (2) Control group: Benign liver lesion cohort — Prospective recruitment of patients with benign liver lesions undergoing surgical treatment at Shandong University Qilu Hospital from June 2025 to June 2028. Inclusion criteria: 1) Age >= 18 years; 2) No claustrophobia, no metal implants (e.g., pacemakers, steel pins, or plates); 3) No severe organ dysfunction of the heart, lungs, liver, kidneys, etc.

Exclusion criteria

Exclusion criteria: (1) Obesity cohort Exclusion criteria: 1) Unable to tolerate the examination or poor image quality; 2) Unable to complete follow-up on time; 3) History of liver malignancy or other malignancies; 4) Previous weight loss surgery. (2) Control Group Exclusion Criteria: 1) Unable to tolerate the examination or poor image quality; 2) History of liver malignancy or other malignant tumours.

Design outcomes

Primary

MeasureTime frame
CT visceral fat and skeletal muscle area;MRI-PDFF liver fat fraction;

Countries

Chian

Contacts

Public ContactDexin Yu

Qilu Hospital of Shandong University

yudexin0330@sina.com+86 185 6008 1629

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026