FindTrial
Sign In

Study on the Preventive and Therapeutic Effects of Age-Matched Donor Milk Supported by a Mutual-Help Human Milk Bank on Bronchopulmonary Dysplasia in Extremely Preterm Infants and the Gut-Lung Axis Mechanism

Study on the Preventive and Therapeutic Effects of Age-Matched Donor Milk Supported by a Mutual-Help Human Milk Bank on Bronchopulmonary Dysplasia in Extremely Preterm Infants and the Gut-Lung Axis Mechanism

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108529
Enrollment
Unknown
Registered
2025-09-01
Start date
2025-12-18
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary Dysplasia (BPD) in Extremely Preterm Infants

Interventions

Experimental group: Early age-matched donor milk group :Feeding extremely preterm infants with donated milk
Control group: Term donor milk group:Feeding term infants with donated milk

Sponsors

Shenzhen Maternity and Child Healthcare Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: EPI with gestational age less than 28 weeks; Admitted within 24 hours after birth; Family members signed the informed consent form and voluntarily participated in the study.

Exclusion criteria

Exclusion criteria: Congenital digestive system malformations (such as congenital intestinal atresia, etc.); Severe infectious diseases (such as sepsis, meningitis, etc.); Severe genetic metabolic diseases.

Design outcomes

Primary

MeasureTime frame
Incidence of bronchopulmonary dysplasia;—

Secondary

MeasureTime frame
Microbial community diversity;Host-microbe interactions;Major nutrients;Protein;Key immunologically active substances;Immunoglobulins;Lactoferrin;—

Countries

China

Contacts

Public ContactXiong Xiaoyun

Shenzhen Maternity and Child Healthcare Hospital

x.xyun@163.com+86 755 8288 9999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026