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Research on the application of self-made skin oxygen therapy device in the prevention and treatment of acute radiation dermatitis of cervical cancer

Research on the application of self-made skin oxygen therapy device in the prevention and treatment of acute radiation dermatitis of cervical cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108515
Enrollment
Unknown
Registered
2025-09-01
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer

Interventions

Experimental group:On the basis of the conventional prevention and treatment measures, the patient was simultaneously treated with a skin oxygen therapy device for local high-flow oxygen therapy from
Medical skin moisturizer spraying, to dry
The oxygen flow rate is set at 6 ~ 8L/min, 2-5 cm away from the skin, and the time is 30min/time, 2 times/day.
Control group:Routine prevention and treatment measures should be given, health education should be strengthened for daily skin care, patients should be required to minimize the irritation and frictio
It is recommended to wear loose, soft and breathable cotton clothing
At the beginning of radiotherapy, medical skin moisturizer preventive spraying should be given, 3 times/d, once in the morning, noon and evening, and it is necessary to avoid half an hour before and a
In the middle of radiotherapy, that is, on the 14th day, recombinant human epidermal growth factor combined with vitamin B12 was sprayed, avoiding half an hour before and after open therapy
Ensure adequate nutritional intake during treatment.

Sponsors

Women's Hospital School of Medicine Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with intermediate and advanced cervical cancer who undergo simultaneous radiotherapy and chemotherapy; 2. Age 40~65 years old, and expected survival > 1 year; 3. The whole body skin is in good condition; 4. BMI index 18.5 ~24.0 kg/m^2; 5. The mental state is normal, and there is no history of mental illness; No ditch barriers; 6. Willing to cooperate with follow-up investigation after discharge.

Exclusion criteria

Exclusion criteria: 1. Accompanied by other systemic diseases and infectious diseases; 2. Skin damage caused by other diseases; 3. Those who have a history of mental illness or mental illness; 4. Obstacles to the ditch; 5. The patient or the patient's family refuses to accept the follow-up investigation after discharge.

Design outcomes

Primary

MeasureTime frame
The degree of damage to the skin (vulva, perianal area, groin, sacrococcygeal, etc.) in the area irradiated by radiotherapy;VAS score;Quality of Life Scale score;

Countries

China

Contacts

Public ContactWang Yang

Women's Hospital School of Medicine Zhejiang University

237092866@qq.com+86 138 1910 6088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026