Perioperative neurocognitive disorders
Conditions
Interventions
Control group:Ginkgo biloba honey ring oral solution placebo, oral, 10ml/time, 3 times a day
Experimental group:Ginkgo biloba honey ring oral liquid, oral, 10ml/time, 3 times a day
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 - 80 years old 2. Hospitalization for coronary artery bypass grafting or heart valve replacement for thoracotomy 3. The patient is currently in stable condition and able to cooperate with the relevant scale assessment 4. Patients or family members sign informed consent
Exclusion criteria
Exclusion criteria: 1. Previously diagnosed with cognitive impairment, dementia, or mental disorders 2. Patients with certain diseases that may interfere with cognitive function evaluation, including those who are addicted to alcohol or who have been diagnosed with drug use or other psychotropic substance abuse by DSM-IV criteria in the past 5 years 3. Those who are unable to perform cognitive evaluation with severe neurological deficits, such as aphasia, severe deafness, blindness, etc 4. Patients with severe cardiac, lung, and renal dysfunction 5. People who are allergic to ginkgo biloba extract and honeydew ring powder 6. Those who have taken ginkgo biloba preparations within 3 months 7. Lactating women 8. Ongoing participation in other studies 9. Other situations that the investigator considers unsuitable for participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA);Mini-Mental State Examination (MMSE);Instrumental Activities of Daily Living (IADL);Ascertain Dementia 8 (AD8); | — |
Countries
China
Contacts
Public ContactYanfang Liu
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed