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Effect of Bupivacaine Liposome in Anterior Saw Muscle Block on Chronic Pain and Pain-Depression after Breast Cancer Surgery

Effect of Bupivacaine Liposome in Anterior Saw Muscle Block on Chronic Pain and Pain-Depression after Breast Cancer Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108495
Enrollment
Unknown
Registered
2025-09-01
Start date
2025-09-22
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain of breast cancer

Interventions

Bupivacaine liposome group:Bupivacaine liposome group used Bupivacaine liposome to block serratus anterior muscle under ultrasound guidance
Ropivacaine group:Ropivacaine group used ropivacaine to block serratus anterior muscle under ultrasound guidance

Sponsors

Xuancheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age>=18. 2.ASA level I~III. 3.Sign informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with a previous history of chronic pain or depression. 2.Patients with coagulation disorders or those who have been taking anticoagulant drugs for a long time. 3.Allergic to local anesthetic drugs. 4.Use of opioids within one month before operation. 5.Patients who are unable to cooperate with nerve block operations.

Design outcomes

Primary

MeasureTime frame
Comorbidity of pain and depression;Postoperative pain;

Secondary

MeasureTime frame
Plasma TNF-a level;

Countries

China

Contacts

Public ContactCao Yahong

Xuancheng People's Hospital

yahongstraw@sina.com+86 150 7791 0035

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026