Chronic pancreatitis
Conditions
Interventions
Phase 1 – Sequence A (DECT?CTP):DECT?CTP (interval ˜15 min)
Phase 1 – Sequence B (CTP?DECT):CTP?DECT (interval ˜15 min)
Phase 2 – 5-min window:DECT?CTP (DECT delayed phase = 5 min)
Phase 2 – 7-min window:DECT?CTP (DECT delayed phase = 7 min)
Phase 2 – 9-min window:DECT?CTP (DECT delayed phase = 9 min)
Phase 2 – 11-min window:DECT?CTP (DECT delayed phase = 11 min)
Phase 2 – 13-min window:DECT?CTP (DECT delayed phase = 13 min)
Phase 2 – 15-min window:DECT?CTP (DECT delayed phase = 15min)
Sponsors
Changhai Hospital, The Navy Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Participants were required to be 18–75 years of age with stable clinical status and an estimated glomerular filtration rate (eGFR) >=30 mL/min/1.73m^2.
Exclusion criteria
Exclusion criteria: Exclusion criteria included unstable clinical status, an eGFR of less than 30 mL/min/1.73m^2, refusal to provide informed consent, pregnancy, a known allergy to iodinated contrast media, inability to perform required breath-holds, or a body weight exceeding 150 kg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ROC AUC of delayed-phase 70-keV VMI for CP vs non-CP (sequence comparison);ROC AUC of delayed-phase iodine density (IMD) across 5/7/9/11/13/15-min windows (optimal window); | — |
Secondary
| Measure | Time frame |
|---|---|
| ROC AUC of combined model (D-IMD + FED [3 s]);Brier score and calibration intercept/slope;Decision-curve analysis standardized net benefit;Image quality (SNR/CNR and artifact score);CTDIvol; | — |
Countries
China
Contacts
Public ContactYun Bian
Changhai Hospital, The Navy Military Medical University
Outcome results
None listed