Functional constipation
Conditions
Interventions
Functional constipation observation group:None
Control group:None
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: FCon patient enrollment criteria: 1. Meet the Rome IV diagnostic criteria for functional constipation; 2. The patient has not received regular treatment for the first time; 3. No analgesics, anesthesia, or sleep aids have been used within one month before enrollment; No antibiotics, prebiotics, probiotics and other products have been used 4. Age 18-70 years old; 5. Right-handed; Normal control group enrollment criteria: 1. Healthy individuals without constipation; 2. Age 18-70 years old; 3. Have not taken any medication within one month before enrollment; 4. No previous history of brain trauma or stroke; 5. No obvious organic lesions on head MRI scan; 6. Right-handed.
Exclusion criteria
Exclusion criteria: FCon patient exclusion criteria: 1. Previous history of abdominal surgery; Patients with secondary constipation; Patients with Hirschsprung's Colon; 2. Central nervous system diseases or serious systemic diseases, such as cardiovascular disease, liver and kidney insufficiency, etc.; History of traumatic brain injury; History of cerebral infarction; 3. History of drug dependence; long-term history of tobacco and alcohol; 4. There are contraindications to MRI examination, such as claustrophobia, metal implants, etc.; 5. Pregnant or lactating women. Normal control group exclusion criteria: 1. History of drug dependence; long-term history of tobacco and alcohol; 2. There are contraindications to MRI examination, such as claustrophobia, metal implants, etc.; 3. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical scale score; | — |
Countries
China
Contacts
Public ContactCai Wangli
Shanghai Tenth People's Hospital
Outcome results
None listed