none
Conditions
Interventions
Remimazolam mesylate group:The remimazolam mesylate group was sedated with remimazolam mesylate
propofol group:The propofol group was sedated with propofol
Sponsors
Wusheng County People's Hospital
Eligibility
Sex/Gender
All
Age
80 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Extremely elderly patients aged 80 or above; 2. ASA classification grades I to IV; 3. Elective surgery is scheduled, and the operation time is no more than 3 hours. 4.18 kg/m ² <= body mass index (BMI) <=28 kg/m ².
Exclusion criteria
Exclusion criteria: 1. Preoperative complications of severe heart, lung, liver and kidney diseases (such as Child-Pugh grade C, cardiac function grade IV); 2. History of severe neuropsychiatric disorders (such as epilepsy, schizophrenia); 3. History of alcohol or drug dependence (such as benzodiazepines).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate (HR), mean arterial pressure (MAP), and BIS values;Total incidence of adverse events;IL-1ß and TNF-a levels; | — |
Countries
China
Contacts
Public ContactTan Xingwen
Wusheng County People's Hospital
Outcome results
None listed