Unresectable or metastatic primary liver cancer
Conditions
Interventions
Observation group:None
Sponsors
The Eighth People‘s Hospital of Jinan
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients with unresectable or metastatic HCC who meet the diagnostic criteria in the 2024 edition of the "Diagnostic Standards for Primary Hepatocellular Carcinoma" and have been confirmed through serum AFP, pathology, or imaging examinations; 2.BCLC B/C, liver function Child-Pugh A grade or better B grade. 3. Age >= 18 years, life expectancy of more than 3 months; 4.ECOG score of 0-1; 5.There should be evaluable lesions, and the evaluation criteria should be in line with the iRECIST standards. 6.The patient has not previously received any systemic anti-cancer treatments for advanced diseases.
Exclusion criteria
Exclusion criteria: 1. Those with an expected survival period of less than 3 months; 2. Patients with concomitant endocrine system disorders; 3. Patients with secondary liver cancer and other malignant tumors, severe cirrhosis, portal hypertension, ascites, Child-Pugh C liver function, coagulation dysfunction, severe cardiovascular and respiratory diseases; 4. Individuals with severe mental or psychological conditions who are unable to cooperate with treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The abnormal change rate of prothrombin and the change rate of the maximum diameter of the tumor after 8 weeks of treatment; | — |
Countries
China
Contacts
Public ContactZhu Tingting
The Eighth People‘s Hospital of Jinan
Outcome results
None listed