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The influence of energy-restricted balanced diet on intestinal barrier function and immune function in overweight/obese patients

Mechanism Research on the Effects of Energy-Restricted Balanced Diet on Immune Function and Intestinal Barrier Function in Obesity

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108426
Enrollment
Unknown
Registered
2025-08-29
Start date
2025-02-18
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight/obese

Interventions

The energy-restricted balanced diet intervention group:A weight loss intervention program based on energy-restricted balanced diet

Sponsors

Ningxia Hui Autonomous Region People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age at 18-65 years (including 18 years and 65 years old) 2. BMI 24.0-40.0kg/m^2 3.Spiritual and cognitive normal, can complete basic communication and communication, can cooperate with research 4. Willingness to be willing Sign the project "Inspector Consent" 5.Living in the local area for at least one year.

Exclusion criteria

Exclusion criteria: 1. There are serious diseases such as heart, liver and kidney, or organs, systems and other diseases, or are currently undergoing severe cardiovascular, immunity, breathing, hepatobiliary, kidney and urology, nerves, muscle skeletal, mental, infection and malignant diseases 2.There are gastrointestinal diseases (such as constipation, diarrhea, abdominal pain, intestinal excitement syndrome, and inflammatory bowel disease) 3.Have taken weight-affecting drugs (inhibitors and appetite suppressants) within the last month. 4.Recently (over the past 2 months) or continuous use of antibiotics 5.Pregnancy and lactation women 6. Plan to participate in other clinical trials 7.Investigators who believe it is inappropriate for other reasons.

Design outcomes

Primary

MeasureTime frame
Biochemical indicator ;Intestinal barrier indicators;Inflammatory markers;Immune indicators;

Secondary

MeasureTime frame
Weight;Waist circumference;Buttocks around ;Body Composition Indicators;

Countries

China

Contacts

Public ContactZhao Qian

Ningxia Hui Autonomous Region People's Hospital

18995160125@163.com+86 189 9516 0125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026