CKD5?MHD
Conditions
Interventions
control group:NA
Dietary factor group:Dietary factor
probiotic + dietary factor group:probiotics+Dietary factors
Sponsors
Wuxi people’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Have received maintenance hemodialysis treatment for more than 3 months; 2.Age: 18-80 years old, gender not limited; 3.Willing to participate after full informed consent.
Exclusion criteria
Exclusion criteria: 1.Antibiotics have been used within one month before enrollment; 2.Taking immunosuppressants, foods or drugs containing probiotics or prebiotic substances at the same time; 3.The primary diseases are systemic lupus erythematosus, vasculitis, autoimmune diseases and those combined with malignant tumors, end-stage liver diseases, and chronic intestinal diseases; 4.Gastrointestinal diseases, including irritable bowel syndrome, Crohn's disease or ulcerative colitis; 5.Pregnant or lactating women. (5) Patients who have been bedridden for a long time are unable to eat by themselves; 6.Patients with combined mental disorders that affect treatment compliance; 7.Unable, unwilling or unwilling to comply with the research requirements, including lifestyle adjustments, follow-up visits and subject responsibilities; 8.Patients with a history of kidney transplantation or those planning to undergo kidney transplantation within six months; 9.Allergy or intolerance to the ingredients of the experimental probiotic product; 10.Patients who are simultaneously undergoing other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum protein-binding toxoids; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factors; | — |
Countries
China
Contacts
Public Contactzhijianzhang
Wuxi people’s Hospital
Outcome results
None listed