Acne
Conditions
Interventions
Test group:The test product MT# 4211133 is used during the trial process.
Sponsors
Shanghai Skin Disease Hospital(Skin Disease Hospital of Tongji University)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Subject is Chinese male or female between 18 and 45 years of age (the proportion of male participants does not exceed 50%), in general good health; 2. Subject has signed an Informed Consent Form; 3. Subject is dependable and agree to adherent to study requirements; 4. Subject presents with a mild to moderate acne condition as the Investigator's Global Assessment (IGA) scale, featuring a minimum of 10 non-inflammatory lesions, along with a minimum of 3 and a maximum of 20 inflammatory lesions (papules and/or pustules); 5. Subject with visible pores scoring at 3-6 on the cheek at screening & baseline visit; 6. Subject with clogged pores scoring at 3-6 on nose and cheek at screening & baseline visit; 7. Subject who has oily skin with forehead Sebumeter test value > 120 µg/cm2 at screening & baseline visit; 8. Subject with tactile roughness scoring at 3-6 on the cheek at screening & baseline visit; 9. Subject with visual roughness scoring at 3-6 on the global face at screening & baseline visit; 10. Subject with redness scoring at 2-6 on the global face at screening & baseline visit; 11. Subject with a lack of radiance scoring at 3-6 on the global face at screening & baseline visit; 12. Subject who agrees to avoid excessive sun exposure during study period and to use sunscreen when exposed to the sun; 13. Subject has routinely used sunscreen (SPF=30) during outdoor activities; 14. Subject who uses facial cleanser without efficacy claims on anti acne and sooth redness; 15. Subject who agrees not wear any other skincare treatment and change the brand of make-up products, other than the assigned test products, during the course of the study.
Exclusion criteria
Exclusion criteria: 1. Subject reports being pregnant or nursing (for females); 2. Subject has any cutaneous disorders which may affect test results (severe acne etc.); 3. Subject is currently using, or has routinely used within one month prior to study initiation, any systemic or topical corticosteroids, vasoconstrictors, antibiotics, anti-inflammatory medications or other dermatological medications; 4. Subject has known allergies to cosmetics, sunscreens, or personal care products; 5. Subject has any facial medical treatments, such as facial peels, photo facials, laser treatments, dermabrasion, botulinum toxin (Botox®), injectable filler treatments, intense pulsed light (IPL), acid treatments etc., which could influence the outcome of the study, in the past 6 months. 6. Subject has participated in any systemic drug study within two weeks of study initiation; 7. Subject is currently using, or has routinely used within two weeks prior to study initiation, any antihistamines; 8. Subject has participated in a clinical or cosmetic study within 1 month of study initiation; 9. Subject has a history of acute or chronic dermatologic, medical, and/or physical conditions which would preclude application of the test product and/or could influence the outcome of the study. 10. Others whose participation in the study is determined inappropriate by the dermatologist or PI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin sebum content; | — |
Secondary
| Measure | Time frame |
|---|---|
| acne count;clinical degree of pore visibility;clinical degree of Clogged pores;clinical degree of Tactile roughness;clinical degree of Visual roughness;clinical degree of Redness;clinical degree of Radiance;clinical degree of Greasiness;Tolerance assessment;Antera 3D measurement parameter;Iscope 30× measurement;keratin content;protein carbonylation; | — |
Countries
China
Contacts
Public ContactChao Yuan
Shanghai Skin Disease Hospital
Outcome results
None listed