Lung Diseases
Conditions
Interventions
Control group:Preoperative normal saline nasal spray
Drug group:Preoperative administration of dexmedetomidine nasal spray.
Sponsors
Qingdao Municipal Hospital
Eligibility
Sex/Gender
All
Age
19 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1: Aged between 18 and 65 years, regardless of gender; 2: Body Mass Index (BMI) between 18 and 30 kg/m^2 3: American Society of Anesthesiologists (ASA) physical status classification I-III. 4: Patients with indications for fiberoptic bronchoscopy requiring non-intubated general anesthesia. 5: Patients informed about the study and who voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1: Mallampati classification grade III or higher, indicating predicted difficult intubation. 2: Comorbidities including severe hypertension, severe arrhythmia, unstable angina, recent acute myocardial infarction, or heart failure. 3: Comorbid neurological, muscular, or psychiatric disorders. 4: Long-term abuse of narcotic analgesics, sedatives, or alcohol addiction. 5: History of gastroesophageal reflux disease or gastric retention. 6: Allergy to any anesthetic drugs used in the study. 7: Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Coughing Response; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital Signs Monitoring;Propofol Dosage and Recovery Time:;Incidence of Respiratory Depression;FOB Procedure Time and Recovery Room Time; | — |
Countries
China
Contacts
Public ContactJunchao Liu
Qingdao Municipal Hospital
Outcome results
None listed