neurogenic lower urinary tract dysfunction concomitant with erectile dysfunction
Conditions
Interventions
Observation group:None
Sponsors
China Rehabilitation Research Center
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Neurological disease. 2. Neurogenic lower urinary tract dysfunction complicated by neurogenic erectile dysfunction. 3. Severe erectile dysfunction refractory to non-surgical therapies, including pharmacologic and rehabilitative interventions.
Exclusion criteria
Exclusion criteria: 1. Extensive bilateral corporal fibrosis or marked congenital penile shortening. 2. Contraindication to the rifampin/minocycline-coated InhibiZone™ AMS 700™ prosthesis, i.e., known hypersensitivity to rifampin, minocycline, or any tetracycline-class antibiotic. 3. Unresolved structural lower urinary tract disease scheduled or anticipated to require surgical correction. 4. Severe systemic disease: advanced heart, lung, hepatic, or renal failure; terminal malignancy; severe coagulopathy or systemic bleeding diathesis; uncontrolled major neurologic or psychiatric disorders. 5. Any other serious condition judged by the investigator to preclude study participation, such as uncontrolled infection or comorbidities likely to interfere with study conduct or outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erection dysfunction inventory of treatment satisfaction,EDITS; | — |
Secondary
| Measure | Time frame |
|---|---|
| International index for erectile function, IIEF;voiding diary;maximum cystometric capacity ;bladder compliance; urinary flow rate;post-void residual urine; | — |
Countries
China
Contacts
Public ContactZhang Fan
China Rehabilitation Research Center
Outcome results
None listed