Fluid overload
Conditions
Interventions
Control group:Increase myocardial contractility, increase organ perfusion pressure, increase the dosage of diuretics and other routine treatments.
Test group(rhBNP group):Recombinant human brain natriuretic peptide+increase myocardial contractility, increase organ perfusion pressure and so on.
Sponsors
The first affiliated hospital of anhui medical university
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Postoperative adult patients after cardiac surgery (age >= 18 years); 2. Fluid overload; 3. Diuretic resistance; 4. Willing to participate in the trial and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Preoperative CKD patients undergoing regular dialysis treatment; 2. Postoperative use of CRRT; 3. Allergic to the drugs involved in this study; 4. Patients with corrected systolic blood pressure still < 90 mmHg after vasopressor treatment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of renal replacement therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospital stay after cardiac surgery;CICU stay time;Tracheal intubation time after cardiac surgery; | — |
Countries
China
Contacts
Public ContactGong Qian
The first affiliated hospital of anhui medical university
Outcome results
None listed