Alzheimers disease
Conditions
Interventions
Oral group:None
Patch group:None
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria (1) Age at least 50 years old, gender not limited; (2) Diagnosed as mild cognitive impairment (MCI) caused by Alzheimer's disease (AD) or Alzheimer's disease(AD); (3) Informed consent and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria (1) Dementia not caused by Alzheimer's disease (such as vascular dementia, Lewy body dementia, etc.); (2) Patients weighing less than 50kg; (3) Combining a history of severe mental illness or epilepsy; (4) Severe liver and kidney dysfunction (ALT/AST>3x upper limit, creatinine clearance rate<30 mL/min); (5) Known to be allergic to Lismedetomidine or patch ingredients. (6) Researchers believe that participants who are not suitable to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of gastrointestinal adverse reactions leading to discontinuation of medication;Incidence of gastrointestinal adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event incidence rate;The incidence of serious adverse events; | — |
Countries
China
Contacts
Public ContactYun Xun
Nanjing Drum Tower Hospital
Outcome results
None listed