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The effect of anxiety on the dose–response relationship of ciprofol in inhibiting body movement during cervical dilation

The effect of anxiety on the dose–response relationship of ciprofol in inhibiting body movement during cervical dilation

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108366
Enrollment
Unknown
Registered
2025-08-28
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anxiety

Interventions

anxiety group:Intravenous injection of ciprofol 0.2mg/kg as the statring dose
non-anxiety group:Intravenous injection of ciprofol 0.2mg/kg as the statring dose

Sponsors

Affiliated Hospital of Shaoxing University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily undergoing painless induced abortion; 2. Aged between 18 and 45 years; 3. Classified as American Society of Anesthesiologists (ASA) I–II; 4. Body mass index (BMI) between 18 and 28 kg/m².

Exclusion criteria

Exclusion criteria: 1. Allergy to opioids and/or propofol; 2. Myasthenia gravis; 3. Schizophrenia or severe depressive disorder; 4. Acute upper respiratory tract infection; 5. History of long-term use of sedative or analgesic medications.

Design outcomes

Primary

MeasureTime frame
In combination with alfentanil, ciprofol inhibits the ED90 of the patient's body movement response when the cervix is dilated;Anxiety scores;

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;Oxygen saturation;Adverse reaction incidence rate;

Countries

China

Contacts

Public ContactBaozhu Cha

Affiliated Hospital of Shaoxing University

ZBZ0202@126.com+86 182 5715 4194

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026