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A Comparative Study on the Short-Term Clinical Outcomes of Minimally Invasive Nonsurgical Therapy (MINST) Versus Conventional Nonsurgical Therapy (CNST) in the Management of Stage III Periodontitis.

A Comparative Study on the Short-Term Clinical Outcomes of Minimally Invasive Nonsurgical Therapy (MINST) Versus Conventional Nonsurgical Therapy (CNST) in the Management of Stage III Periodontitis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108359
Enrollment
Unknown
Registered
2025-08-28
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stage III periodontitis

Interventions

control group:minimally invasive non-surgical periodontal therapy (MINST)
test group:conventional non-surgical periodontal therapy(CNST)

Sponsors

Jiangsu Province(Suqian)Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 70 years, regardless of gender. 2. In good general health and able to participate in examinations throughout the study period. 3. Diagnosis of Stage III periodontitis according to the 2018 classification of periodontal diseases jointly proposed by the American Academy of Periodontology (AAP) and the European Federation of Periodontology (EFP), meeting all of the following criteria: Severity: Clinical attachment loss (CAL) >= 5 mm at the site with the greatest interproximal loss; radiographic bone loss (RBL) extending to the middle third of the root or beyond; = 6 mm in the full dentition; vertical bone loss >= 3 mm; Class II or III furcation involvement (FI); presence of moderate alveolar ridge defects. Extent and distribution: Localized (=30% of teeth involved). 4. The number of remaining teeth in the oral cavity must be no less than 20.

Exclusion criteria

Exclusion criteria: 1. Smoking; 2. Presence of systemic diseases, such as diabetes or autoimmune disorders; 3. History of periodontal treatment within 6 months prior to baseline examination; 4. Use of antibiotics within 1 month prior to baseline examination; 5. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
clinical attachment level (CAL);Percentage of sites with positive bleeding on probing (BOP);probing depth (PD);plaque index (PLI);Incidence of postoperative dentin hypersensitivity.;Visual Analogue Scale (VAS) score for postoperative pain and its duration.;Number of sites with probing depth >= 5 mm and positive bleeding on probing.;gingival recession (GR);—

Secondary

MeasureTime frame
Oral Health Impact Profile-14 (OHIP-14) score;—

Countries

China

Contacts

Public ContactXiaofan Cheng

Jiangsu Province(Suqian)Hospital

2021250107@stu.njmu.edu.cn+86 15151820956

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026