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The Effect of Different volume of crystalloid Co-loading on the Phenylephrine Requirement to Prevent Spinal-anesthesia induced hypotension During Elective Cesarean Section

The Effect of Different volume of crystalloid Co-loading on the Phenylephrine Requirement to Prevent Spinal-anesthesia induced hypotension During Elective Cesarean Section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108341
Enrollment
Unknown
Registered
2025-08-28
Start date
2025-10-23
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia induced hypotension

Interventions

5 mL/kg crystalloid co-loading:5 mL/kg crystalloid co-loading
15 mL/kg crystalloid co-loading:15 mL/kg crystalloid co-loading

Sponsors

Ningbo University Affiliated Women's and Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: According to the standards set by the American Society of Anesthesiologists (ASA), this study included pregnant women classified as ASA I or II, all of whom were undergoing elective cesarean sections at full term with a singleton pregnancy. The participants had a height ranging from 150 to 170 cm and a BMI of less than 30.

Exclusion criteria

Exclusion criteria: Contraindications for epidural anesthesia include fetal distress, twin pregnancies, premature rupture of membranes, and placenta previa. Other maternal comorbidities such as obesity (BMI = 30), pregnancy-related hypertension, preeclampsia, liver dysfunction, diabetes, and cardiopulmonary insufficiency should also be considered.

Design outcomes

Primary

MeasureTime frame
Effective or ineffective dose of preventing phenylephrine;

Secondary

MeasureTime frame
pH of Umbilical Arterial Blood;

Countries

China

Contacts

Public ContactZhu Xiatian

Ningbo University Affiliated Women's and Children's Hospital

784518279@qq.com+86 158 8856 2428

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026