Patients who required bronchoscopy due to respiratory diseases.
Conditions
Interventions
Magnesium sulfate group:Magnesium sulfate 40 mg/kg+ propofol 1.5mg/kg+ sufentanil 0.1µg/kg
Control group:Propofol 1.5mg/kg+ sufentanil 0.1µg/kg
Sponsors
The First People's Hospital of Yancheng
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Age: 18-80; 2: BMI:18.5-28 kg/m^2; 3: Patients classified as ASA physical status I–III who underwent painless bronchoscopy.
Exclusion criteria
Exclusion criteria: 1: Patients who are allergic to sedative/anesthetic drugs such as sufentanil, propofol, magnesium sulfate, or have a history of severe allergies in the past; 2: Patients with severe cardiovascular or cerebrovascular diseases—such as acute coronary syndrome, significant arrhythmias, heart failure, uncontrolled hypertension (SBP >=180 mmHg or DBP >=110 mmHg), or a history of stroke; 3: Patients with preoperative respiratory failure, difficult airway, severe sleep apnea syndrome or STOP-Bang score >=5; 4: Patients with severe anemia (hemoglobin <6 g/dL) or a platelet count < 50 × 10?/L; 5: Patients with cognitive dysfunction and who were unable to communicate effectively; 6: Patients with a history of psychotropic drug or anesthetic abuse ; 7: Severe liver and kidney dysfunction; 8: Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interruption rate of bronchoscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough score;Incidence of respiratory depression;Incidence of bradycardia;Incidence of hypotension;Incidence of PONV;The dosage of propofol;Awakening time;Duration of stay in the PACU;Patients’ serum magnesium concentration within 24 hours postoperatively; | — |
Countries
China
Contacts
Public ContactLiu Xiang
The First People's Hospital of Yancheng
Outcome results
None listed