Digestive tract tumors that cannot be treated with radical surgery or recurrence and metastasis after surgery
Conditions
Interventions
Umbilical cord blood mononuclear cell infusion combing with chemotherapy group:Infusion of Umbilical cord blood mononuclear cell
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age from 18 years old to 70 years old; 2.Patients diagnosed with digestive tract tumors that cannot be treated with radical surgery or recurrence and metastasis after surgery; 3.Karnofsky score greater than 60; 4.Voluntarily participate in this study and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Having severe mental illness; 2.Having heart, lung, kidney and other organ failure; 3.Severe infections requiring intravenous antibiotics, antifungal or antiviral therapy; 4.Combining with other fatal and dangerous diseases; 5.Vulnerable groups, including people with mental illness, cognitive impairment, critically ill patients, minors, pregnant women, illiterates, etc;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of peripheral blood immune cells (T cell subsets, B cells, and NK cells);Subject's quality of life;Serum complement and immunoglobulin content were examined; | — |
Secondary
| Measure | Time frame |
|---|---|
| PFS;ORR;OS;RPS; | — |
Countries
China
Contacts
Public ContactZhiwei Liu
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed