Geriatric depression
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Initial onset age of 60 years or older; 2. Meeting the diagnostic criteria for depressive disorders as outlined in the Diagnostic and Statistical Manual of Mental Disorders-5th Edition (DSM-5); 3. A total score of 17 or higher on the Hamilton Depression Rating Scale-17 (HAMD-17); 4.Educational attainment of at least primary school level, capable of cooperating to complete assessment examinations; 5.A score of less than 26 on the Montreal Cognitive Assessment (MOCA); 6. Written informed consent obtained from the individual or their family.
Exclusion criteria
Exclusion criteria: 1. A history of previous cranial diseases, brain injuries, epileptic seizures, and other neurological diseases; 2. Having severe or unstable cardiovascular, respiratory, immune, or other systemic diseases; 3. A history of or current diagnosis via DSM-5 of the following mental illnesses: organic mental disorders, Alzheimer's disease, secondary dementia caused by other reasons, schizophrenia, schizoaffective disorder, bipolar affective disorder, delusional disorder, unspecified mental illness, alcohol (or drug) dependence or abuse, and personality disorders; 4. Having contraindications to nuclear magnetic resonance or transcranial magnetic therapy: such as having electronic or metal implants in the body (dentures, arterial clips, pacemakers, or metal fixators, etc.), claustrophobia, etc.; 5. Depressive states caused by other systemic diseases and organic brain lesions; 6. A history of alcohol or morphine drug abuse;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depressive symptom ; | — |
Secondary
| Measure | Time frame |
|---|---|
| cognitive function; | — |
Countries
China
Contacts
Beijing Anding Hospital, Capital Medical University