Gynecologic Laparoscopic Ovarian Cyst Surgery
Conditions
Interventions
Experimental group:Following specimen resection, the intravenous dose of oliceridine for the first enrolled patient was set at 20 µg·kg?1. Subsequent patients' doses were adjusted based on the precedi
if no pain occurred, the dose had an 89% probability of remaining unchanged and an 11% probability of increasing by 5 µg·kg?1. If moderate-to-severe pain was observed in the 45 µg·kg?1 group or no pai
Sponsors
Anqing Municipal Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 65 years; (2) Patients scheduled to undergo elective gynecologic laparoscopic surgery; (3) Body mass index (BMI) between 18 and 32 kg/m²; (4) Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: (1) History of sedative or analgesic abuse; (2) Allergy or intolerance to anesthetic agents; (3) Hearing or speech impairment precluding effective communication; (4) Pre-existing severe cardiac/pulmonary dysfunction, hepatic/renal insufficiency, uncontrolled hypertension/diabetes, or other organ dysfunction with ASA physical status >III; (5) Patient and/or legal guardian refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether moderate-to-severe acute pain occurred within 1 hour after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS scores at 2h, 6h, 12h, and 24h postoperatively;Number of rescue analgesic administrations within 24 hours postoperatively;QoR-15 scale scores at 24 hours postoperatively;Time to first postoperative flatus;Incidence of adverse reactions including postoperative nausea and vomiting (PONV); | — |
Countries
China
Contacts
Public ContactDuan Jinjuan
Anqing Municipal Hospital
Outcome results
None listed