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The influence of unilateral high-frequency repetitive transcranial magnetic stimulation on dysphagia and functional magnetic resonance imaging in stroke

The influence of unilateral high-frequency repetitive transcranial magnetic stimulation on dysphagia and functional magnetic resonance imaging in stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108286
Enrollment
Unknown
Registered
2025-08-27
Start date
2023-11-11
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Experimental group:For rTMS treatment, the coil was placed over the contralesional cerebral hemisphere at the same stimulation site for the mylohyoid muscle. The coil was kept tangential to the skull
Sham stimulation group:Sham rTMS was delivered using the same stimulation sites and parameters as rTMS. The protocol was identical to that of the rTMS group. However, during treatment, the coil was po

Sponsors

The Second Affiliated Hospital of Jiaxing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 80 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosis of stroke meeting the revised criteria set by the 4th National Stroke Conference, and confirmed by imaging; 2.First-time onset, age =3, an SSA score of >=24, and an MMASA score of <=95; 5.Disease duration <= 6 months, able to cooperate with examinations and treatment; 6.Informed consent obtained from both the patient and their family prior to study inclusion; 7.Right-handed with normal vision.

Exclusion criteria

Exclusion criteria: 1.Dysphagia caused by other neurological conditions, such as traumatic brain injury, head and neck tumors, psychiatric disorders, Parkinson’s disease, or motor neuron diseases; 2.Lesions present in both cerebral hemispheres or both sides of the brainstem, with the primary lesion not confined to one side; 3.Damage to vital organs or severe underlying conditions, such as malignant tumors; 4.Tendency towards coma or bleeding; 5.Contraindications for rTMS (intracranial metal implants, pacemaker implants, history of epilepsy, pregnancy, breastfeeding, or intracranial drainage tubes); 6.Onset of a major illness or life-threatening condition during treatment; 7.Excessive head movement during MRI scanning that interferes with data collection.

Design outcomes

Primary

MeasureTime frame
Resting-state fMRI index(ALFF, fALFF ,PerAF,Graph theory analysis);Swallowing Function;Eating ;Mann Assessment of Swallowing Ability;

Countries

China

Contacts

Public ContactXuting Chen

The Second Affiliated Hospital of Jiaxing University

1791949296@qq.com+86 197 0385 5037

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026