Patients undergoing laparoscopic cholecystectomy under general anesthesia
Conditions
Interventions
Control group:Mechanical ventilation was performed with a conventional tidal volume setting of 8 ml/kg
Experimental group:The tidal volume setting for mechanical ventilation is based on the measured value at the preoperative resting state
Sponsors
The Affiliated Hospital of Inner Mongolia Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: A total of 40 patients scheduled for elective laparoscopic cholecystectomy at the Affiliated Hospital of Inner Mongolia Medical University between August 2024 and January 2025 were enrolled. The patients ranged in age from 30 to 50 years, with a body mass index (BMI) between 18 and 24 kg/m^2 and were classified as American Society of Anesthesiologists (ASA) physical status I–II. Surgical duration was limited to within 1.5 hours
Exclusion criteria
Exclusion criteria: (1) hypoxemia (partial pressure of oxygen, PaO2 50 mmHg), or central hypoventilation syndrome; (2) a history of severe arrhythmia, significant cardiac, pulmonary, hepatic, or renal dysfunction, or circulatory instability with decompensated cardiac function; (3) coagulopathy (international normalized ratio [INR] > 1.5); (4) recent or uncontrolled infections or excessive airway mucus secretion; (5) patients assessed preoperatively by anesthesiologists as having difficult airway management or those at high risk for gastric content reflux or aspiration; (6) abnormal airway anatomy, previous tracheotomy, or lobectomy; (7) neurological disorders impairing cooperation; (8) intraoperative blood loss exceeding 1000 mL or vital sign fluctuations beyond the normal range requiring pharmacological intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HTI56;SP-A;IL-6;TNF-a; | — |
Countries
China
Contacts
Public ContactXin Wang
The Affiliated Hospital of Inner Mongolia Medical University
Outcome results
None listed