Atrial fibrillation
Conditions
Interventions
Phlegmatic Atrial Fibrillation Group:None
Non-Phlegmatic Atrial Fibrillation Group:None
Phlegmatic Healthy People Group:None
Sponsors
Xiyuan Hospital, China Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients with atrial fibrillation: 1. Age: 30-75 years old, gender not limited;2. The history of paroxysmal atrial fibrillation should be no less than 6 months, and there should be atrial fibrillation attacks in the past 3 months.3. It meets the diagnostic criteria for "palpitations with phlegm-heat and blood stasis obstruction syndrome".4. Sign the informed consent form;Subjects who met 1.2.3.4 were included in the group with phlegm-heat and blood stasis obstruction syndrome for paroxysmal atrial fibrillation, and those who met 1.2.4were included in the group without phlegm-heat and blood stasis obstruction syndrome for paroxysmal atrial fibrillation. Inclusion criteria for healthy subjects: 1. Age: 30-75 years old, gender not limited;2. Sinus rhythm, normal electrocardiogram;3. Normal blood and urine routine tests, liver and kidney functions;4. Sign the informed consent form;
Exclusion criteria
Exclusion criteria: Exclusion criteria for atrial fibrillation patients: 1. Those with underlying heart diseases such as coronary heart disease, cardiomyopathy, and valvular heart disease;2. Those with chronic diseases such as hyperthyroidism, autoimmune diseases, and malignant tumors;3. Patients with acute or chronic infectious diseases;4. Those who have had surgery within the past two months;5. For those with severe liver and kidney dysfunction, creatinine is greater than 177umol/L, and transaminase is more than three times the normal value;6. Pregnant or lactating women and those with mental disorders who are unable to cooperate. Exclusion criteria for healthy subjects: 1. Those with a history of chronic diseases in the respiratory system, circulatory system, blood system, endocrine system, etc.2. Those who have a history of acute or chronic infections within the past month;3. Pregnant or lactating women and those with mental disorders who are unable to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin 17;Interleukin 6;Nuclear factor kappa-B;Tumor necrosis factor a; | — |
Secondary
| Measure | Time frame |
|---|---|
| NOD-like receptor thermal protein domain associated protein 3;Galectin-3;Haematology + c reactive protein;Lipid Panel Screen;Liver and kidney function;Urine routine; | — |
Countries
China
Contacts
Public ContactDazhuo Shi
Xiyuan Hospital, China Academy of Traditional Chinese Medicine
Outcome results
None listed