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Comparative study of uterine artery embolization and hysterectomy in the treatment of symptomatic adenomyosis

Comparative study of uterine artery embolization and hysterectomy in the treatment of symptomatic adenomyosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108252
Enrollment
Unknown
Registered
2025-08-27
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenomyosis, dysmenorrhea, menorrhagia

Interventions

The UAE group:NA
Laparoscopic hysterectomy group:NA

Sponsors

Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Symptomatic adenomyosis without fertility requirements, with symptoms defined as menorrhagia, dysmenorrhea and/or pain related to uterine volume and pain unrelated to the menstrual cycle. 2. Diagnosed by ultrasound or magnetic resonance imaging (MRI) as simple adenomyosis or adenomyosis as the main condition accompanied by uterine fibroids or ovarian chocolate cysts; 3. These women had received drug treatment but it was unsuccessful, or they decided that drug treatment was not feasible, or they refused drug or other treatments.

Exclusion criteria

Exclusion criteria: 1. The acute phase of concurrent urogenital system infection or systemic infection; 2. Coexisting confirmed or suspected gynecological malignancies; 3. The acute stage of severe internal diseases such as heart, liver and kidney failure; 4. Severe coagulation disorders and hematological diseases; 5. Those who need to undergo total hysterectomy through laparotomy for various reasons. 6. Patients undergoing laparoscopic total hysterectomy concurrently with severe endometriosis surgery or bilateral oophorectomy; 7. Laparoscopic hysterectomy group: There were other conditions that made them unable to tolerate anesthesia and surgery. 8. The UAE group: General contraindications for interventional embolization therapy, such as contrast agent allergy, skin infection at the puncture site, renal insufficiency or severe immunosuppression of the body; 9. The UAE group: Patients with adenomyosis whose lesions were mainly supplied by bilateral ovarian arteries as indicated by MRA.

Design outcomes

Primary

MeasureTime frame
Quality of life and health status score;

Secondary

MeasureTime frame
pain score;Symptoms and health-related quality of life scores;

Countries

China

Contacts

Public ContactWenjiang Wei

Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)

147weiwenjiang@sina.com+86 20 8916 9379

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026