Non-obstructive Azoospermia (NOA)
Conditions
Interventions
Gold Standard:Cytological examination during microdissection testicular sperm extraction (mTESE) and postoperative pathology
Index test:Predictive Model for the Diagnosis and Classification of Spermatogenesis Disorders
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with non-obstructive azoospermia (NOA), confirmed by at least two consecutive semen centrifugations showing no sperm and undergoing their first microdissection testicular sperm extraction (mTESE) procedure.
Exclusion criteria
Exclusion criteria: 1.Hypothalamic-pituitary-gonadal (HPG) axis dysfunction, such as hypogonadotropic hypogonadism or severe thyroid dysfunction; 2.Bilateral Obstruction of the Reproductive Tract; 3.Uncontrolled urinary and reproductive system infections or tumors; 4.Repeated microdissection testicular sperm extraction (mTESE) procedures; 5.Not using standard techniques for microdissection testicular sperm extraction; 6.Other factors deemed unsuitable for inclusion in the study by the researchers;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sex hormone;Testicular volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| karyotype; | — |
Countries
China
Contacts
Public ContactZheng Li
Shanghai General Hospital
Outcome results
None listed