Biliary strictures patients
Conditions
Interventions
No sphincterotomy group:After successful cannulation, standardized ES will not be performed, then proceed with subsequent ERCP operations
Sphincterotomy group:After successful cannulation, standardized ES was performed using a sphincterotome with blended current, then proceed with subsequent ERCP operations
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adults aged >=18 years; 2. In patients with biliary stricture, ERCP (endoscopic retrograde cholangiopancreatography) is required to place a transpapillary biliary stent (primary ERCP, primitive duodenal papilla). 3. Be able to understand and comply with the clinical research protocol, and voluntarily sign the informed consent
Exclusion criteria
Exclusion criteria: 1. Patients with biliary stent placement above the nipple. 2. History of gastrointestinal reconstruction surgery (except Billroth type I). 3. The presence of acute pancreatitis. 4. The main duodenal papilla could not be reached during ERCP. 5. Duodenal papilla biliary fistula, ectopic duodenal papilla, pancreaticobiliary maljunction and annular pancreas may affect the operation. 6. Severe acute cholangitis. 7. Prothrombin time and international normalized ratio (INR) >=1.5, and platelet count <50,000/mm³. 8. Severe heart, lung, brain disease, severe liver disease (Child-Pugh score B-C), severe renal insufficiency (requiring maintenance hemodialysis). 9. Anticoagulation or antiplatelet agents cannot be stopped. 10. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PEP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of bleeding after ERCP;Incidence of cholangitis after ERCP;Recurrence rate of biliary obstruction;Incidence of Cholecystitis after ERCP; | — |
Countries
China
Contacts
Public ContactJunbo Hong/Xiaojiang Zhou
The First Affiliated Hospital of Nanchang University
Outcome results
None listed