Hypertrophic Cardiomyopathy
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Diagnosed with end-stage heart failure, fulfilling one or more of the following criteria: (1) NYHA functional class III–IV; (2)Left ventricular ejection fraction (LVEF) <= 20%; (3)Requirement for long-term mechanical circulatory support; 3. Scheduled to undergo heart transplantation; 4. Informed consent obtained.
Exclusion criteria
Exclusion criteria: 1. Inability to obtain usable tissue samples due to surgical failure or delay; 2. A prior history of systemic diseases that significantly impair cardiac function but are unrelated to metabolic disorders (e.g., severe immune system diseases).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Steroid receptor coactivator-Interacting Protein, SIP;Peroxisome Proliferator-Activated Receptor ?, PPAR?; | — |
Countries
China
Contacts
Public ContactWu Jianbo
The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
Outcome results
None listed