Traumatic splenic rupture
Conditions
Interventions
Microwave ablation (MWA) group:Microwave Ablation for Spleen Preservation
Autologous transplantation (AST) group:Splenectomy with autologous spleen transplantation
Splenectomy Group:Splenectomy
Sponsors
Suining Hospital of Traditional Chinese Medicine Affiliated with North Sichuan Medical College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Definitive Diagnosis: Traumatic splenic rupture was confirmed in all cases using abdominal CT scan, with additional assessment by eFAST ultrasound when indicated. Diagnostic peritoneal aspiration was performed in cases where imaging findings required further clarification. 2. Surgical Indications: Enrollment required fulfillment of >=2 criteria: (1) AAST grade III-IV parenchymal injury; (2) persistent hemodynamic instability (systolic blood pressure 20 minutes or vasopressor requirement); (3) radiographic evidence of >=600 mL intraperitoneal hemorrhage; (4) failure of nonoperative management. 3. Operational Feasibility: Anatomic eligibility demanded either: (1) sufficient residual parenchyma for MWA (>=30% viable tissue post-ablation) (2) adequate quality splenic tissue for AST (>=10 transplantable fragments). 4. Ethical Compliance: Formal inclusion mandated documented written informed consent from patients or legal guardians, coupled with complete 90-day postoperative follow-up data.
Exclusion criteria
Exclusion criteria: 1. Anatomical & Pathological Exclusions: (1) preoperative identification of functional accessory spleens, (2) preexisting conditions mandating splenectomy, including hematologic disorders and primary/metastatic splenic malignancies. 2. Clinical Contraindications: (1) concurrent hollow viscus perforation; (2) active intra-abdominal infection; (3) life-threatening polytrauma requiring emergent intervention for associated injuries. 3. Protocol Deviations: Patients exceeding damage control parameters (>1000 mL blood loss during procedure or >4 hours operative time) were excluded. 4. Follow-up Compliance: Exclusion applied to patients with either incomplete perioperative records or inadequate 60-day postoperative follow-up documentation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative Metrics: Skin-to-skin time (minutes), estimated blood loss (mL, suction+gauze weight);Technical Success;60-day postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Splenic function;Structural Preservation;Clinical Outcomes;Recovery Quality; | — |
Countries
China
Contacts
Public ContactJian Du
Suining Hospital of Traditional Chinese Medicine Affiliated with North Sichuan Medical College
Outcome results
None listed