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The effect of dual target iTBS combined with lower limb rehabilitation robot assisted training on post-stroke walking function and brain motor network: a clinical randomized controlled study

A randomized controlled study of single target and dual target iTBS combined with lower limb rehabilitation robot assisted training on walking function in post-stroke patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108232
Enrollment
Unknown
Registered
2025-08-27
Start date
2025-08-27
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post stroke

Interventions

Control group:Lower limb rehabilitation robot combined with single-target iTBS
Experimental group:Lower limb rehabilitation robot combined with dual-target iTBS

Sponsors

Zhejiang Rehabilitation Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for stroke and confirm by CT or MRI; (2) Age 30-75 years old (including boundary value), male or female (3) First onset, the course of the disease is 1-6 months after stroke; (4) The patient had modified lower extremity Ashworth grade = III (5) Standing balance >= level 2; FAC >= Level 2; (6) Able to understand and follow instructions: (7) Stable condition.

Exclusion criteria

Exclusion criteria: (1) Those who are accompanied by severe cognitive impairment and speech impairment and cannot cooperate with training; (2) Those who are partially blind and have visual impairment; (3) Vestibular dysfunction such as vertigo and tinnitus; (4) Those who are accompanied by severe bone and joint diseases and severe cardiopulmonary diseases and cannot be trained; (5) Those whose condition worsens; (6) Skull absence.

Design outcomes

Primary

MeasureTime frame
Functional NIR spectroscopy technology;3D Gait Analysis;Quantitative electroencephalogram;Fugl-Meyer assessment lower extremity;Functional ambulation category scale;Berg balance scale;Time up and go test;Six minutes walk test;

Countries

China

Contacts

Public ContactZhang Wanying

Zhejiang Rehabilitation Medical Center

467886664@qq.com+86 139 6747 6181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026