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Metagenomic and metabolomic analyses reveal the pathogenisis of paranasal sinus fungal ball

Metagenomic and metabolomic analyses reveal the pathogenisis of paranasal sinus fungal ball

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108224
Enrollment
Unknown
Registered
2025-08-27
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fungal ball sinusitis

Interventions

Patients with fungal ball sinusitis:NA
Patients with simple nasal septum deviation:NA

Sponsors

Bejing Tongren Hospital, Capital Medical Uniersity
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients who were diagnosed with fungal ball sinusitis; 2. Patients diagnosed with simple nasal septum deviation (as control group);

Exclusion criteria

Exclusion criteria: 1. Local or systemic use of antibiotics and hormone drugs within the past one month; 2. Age between 18 and 70 years old; 3. Nasal irrigation within two weeks; 4. Imaging examination showed inflammation of ostiomeatal complex; 5. Patients with severe respiratory diseases, chronic wasting diseases, tumors and immunodeficiency; 6. Patients with allergic rhinitis; 7. Patients with congenital ciliary dysfunction;

Design outcomes

Primary

MeasureTime frame
Classification of metabolites;Differential genes and functions;Composition and relative abundance of microbial species;

Countries

China

Contacts

Public ContactYunchuan Li

Bejing Tongren Hospital, Capital Medical Uniersity

1964liyunchuan@163.com+86 15910719333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026