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Determination of the Median Effective Dose (ED50) of Ciprofol Combined with Sufentanil for Painless Gastroscopy in Abdominally Obese Patients

Median Effective Dose (ED50) of Sufentanil Combined with Different Drugs for Gastroscopy in Various Populations

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108186
Enrollment
Unknown
Registered
2025-08-26
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroscopy

Interventions

Group 2(Normal size population):Ciprofol
Group 1(People with abdominal obesity):Ciprofol

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing upper gastrointestinal endoscopy under intravenous anesthesia; 2.ASA grade: I, II, III; 3. Both sexes, aged >=18 years old; 4. Those who can understand the trial protocol and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Contraindications to sedation/anesthesia; 2. Have contraindications to endoscopy (such as acute upper respiratory tract infection, asthma attack, abnormal liver function, etc.); 3. Known to be allergic to eggs, soy products, opioids and their rescue drugs; Difficult airway and hemodynamic instability (e.g., systolic blood pressure 180 mmHg, diastolic blood pressure > 110 mmHg, modified Mallampati class III or IV, or SpO2 < 90% on air inhalation); 5. Obstructive sleep apnea syndrome; 6. Participated in other drug trials within 3 months before the study.

Design outcomes

Secondary

MeasureTime frame
Blood pressure;Heart rate;SpO2;Adverse Events;

Primary

MeasureTime frame
Anesthesia Efficacy Evaluation;

Countries

China

Contacts

Public ContactXiaopeng Mei

The First Affiliated Hospital of Xi'an Jiaotong University

meixpxp126@126.com+86 181 6192 9067

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026