Oral leukoplakia
Conditions
Interventions
Experimental Group:Thymopeptides enteric-coated tablets (15 mg once daily (qd) for 3 months) and 2% sodium bicarbonate solution gargle (10 mL three times daily (tid) fo
Control Group:2% sodium bicarbonate solution gargle (10mL three times daily (tid) for 3 months)
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Histopathological diagnosis of oral vitiligo; 2. Age>=18 years (male and female; excluding pregnant or lactating women and women planning to become pregnant within 2 years), voluntarily participate in this study and sign the subject's informed consent form; 3. No use of immunomodulatory drugs or systemic antifungal therapy within 3 months.
Exclusion criteria
Exclusion criteria: 1. Vitiligo biopsy is severely abnormal hyperplasia or has become cancerous; 2. Received other immunotherapy within 3 months; 3. Contraindications to the use of thymus peptide or sodium bicarbonate; 4. Systemic disease that is not effectively controlled.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective mitigation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral toluidine blue staining results;Oral autofluorescence results;Safety assessment; | — |
Countries
China
Contacts
Public ContactZhou Yu
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed