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The effect of oliceridine fumarate combined with propofol in the anesthesia application for painless hysteroscopy

The effect of oliceridine fumarate combined with propofol in the anesthesia application for painless hysteroscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108170
Enrollment
Unknown
Registered
2025-08-26
Start date
2025-08-26
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscope

Interventions

The Oliceridine Group:General anesthesia is administered with oliceridine fumarate combined with propofol.
Sufentanil group:General anesthesia is administered with sufentanil combined with propofol.
Fentanyl group:General anesthesia is administered with fentanyl combined with propofol.

Sponsors

People's Hospital of Guilin City
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Screen patients aged between 18 and 65 years old (inclusive); (2) Subjects undergoing elective hysteroscopic polypectomy under intravenous general anesthesia; (3) ASA physical status classification I-II; (4) Body Mass Index (BMI) between 18 kg/m^2 and 30 kg/m^2 (inclusive); (5) Subjects fully understand the purpose, content, procedures and risks of this trial, voluntarily participate in the clinical trial and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients who cannot understand the Clinical Recovery Score (CRS) upon awakening and cannot cooperate with the evaluation; (2) Patients with a history of pain who have been taking painkillers for a long time; (3) Patients with severe cardiovascular diseases; (4) Patients allergic to oliceridine, fentanyl, or sufentanil; (5) Patients who withdraw from the study midway.

Design outcomes

Primary

MeasureTime frame
MOAA/S score;CRS Score;Postoperative Awakening Time;Time to complete recovery of consciousness;

Secondary

MeasureTime frame
respiratory rate;heart rate;blood pressure;oxygen saturation;Incidence Rate of Adverse Events;

Countries

China

Contacts

Public ContactZhang Wenbin

People's Hospital of Guilin City

wenbinzh2008@163.com+86 136 3519 6690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026