critical infection
Conditions
Interventions
Infectious Non-Septic Group:None
Sepsis Group:None
Severe Non-Infectious Group:None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Total length of ICU stay >= 24 hours; 3. APACHE II score >= 15 points; 4. Serum/plasma samples suitable for sST2 testing were collected within 24 hours of new-onset sepsis; 5. Availability of complete baseline clinical data (demographics, vital signs, underlying diseases) and key outcome data (60-day survival status, length of ICU stay, etc.); 1. Age >= 18 years old; 2. Met the diagnostic criteria for sepsis-3.0 at the time of ICU admission 3. New-onset sepsis occurred within 24 hours before ICU admission, with a total length of ICU stay >= 48 hours; 4. APACHE II score = 15 points; 5. For patients in the sepsis group (Group C), at least two serum/plasma samples suitable for sST2 testing were collected within 48 hours of disease onset (the first sample within 24 hours, and the second sample between 24 and 48 hours); 6. Availability of complete baseline clinical data (demographics, vital signs, underlying diseases) and key outcome data (60-day survival status, length of ICU stay, etc.);
Exclusion criteria
Exclusion criteria: 1. Death or discharge against medical advice within 24 hours of ICU admission. 2. Advanced-stage malignant tumor. 3. Patients with known chronic cardiac insufficiency (NYHA class III-IV) or recent (within 3 months) acute heart failure exacerbation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 60-day mortality;Survival time within 60 days; | — |
Countries
China
Contacts
Public ContactYunliang Tu
Peking University Shenzhen Hospital
Outcome results
None listed