Postoperative Pain after Spinal Surgery
Conditions
Interventions
Group A: Dezocine + Sufentanil Group :PCIA uses 0.3mg/kg dezosine 2ug/kg sufentanil 0.2mg/kg ondansetron
Group B: Flurbiprofen Axetil + Sufentanil Group :PCIA uses flurbiprofen ester 200mg 2ug/kg sufentanil 0.2mg/kg ondansetron
Group C: Dezocine + Sufentanil + Flurbiprofen Axetil Group:PCIA uses 0.15 mg/kg dezoxin, flurbiprofen ester 150 mg, 1ug/kg sufentanil, and 0.2 mg/kg ondansetron
Sponsors
The Third Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age>=65 years old, <=85 years old; 2. ASA grade I-III; 3. Thoracolumbar spinal fusion and internal fixation surgery (1 to 2 segments); 4. The operation takes more than 1 hour and is less than 3 hours; 5. All patients signed the informed consent form with the approval of the hospital ethics committee.
Exclusion criteria
Exclusion criteria: 1. Patients who have had any cerebrovascular accident within 3 months, such as stroke, transient ischemic attack, etc.; 2. Those who have contraindications or allergies to the test drug and other anesthetic drugs; 3. History of neurological diseases; History of chronic pain; drug addiction and alcoholism; History of long-term opioid use; 4. Patients with severe organic lesions (coronary heart disease, severe hypertension, severe blood system dysfunction, abnormal liver and kidney function) during preoperative examination; 5. Body mass index (BMI) less than 18kg/m^2 or >=28kg/m^2; 6. Patients who have participated in other clinical trials within one month before the start of this study; 7. Patients with other conditions that the investigator deems unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS Resting and Activity Pain Scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Beck Depression Inventory (BDI);Zung Self-Rating Anxiety Scale (SAS) Score;Ramsay Score; | — |
Countries
China
Contacts
Public ContactLiang Qingchun
The Third Affiliated Hospital of Southern Medical University
Outcome results
None listed