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Study on risk factors of small intestinal bacterial overgrowth after gastrointestinal surgery based on real-world data

Study on risk factors of small intestinal bacterial overgrowth after gastrointestinal surgery based on real-world data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108153
Enrollment
Unknown
Registered
2025-08-26
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive tract diseases

Interventions

Observation group:NA

Sponsors

Putuo People’s Hospital, School of Medicine, Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age is 18 years old or above, with no gender restrictions; 2.Patients admitted to the General Surgery Department of Putuo People’s Hospital, School of Medicine, Tongji University and transferred to the general ward after completing digestive surgery for various diseases; 3.Including open surgery and laparoscopic surgery; 4.Having a standard classification III or better physical condition established by the American Society of Anesthesiologists, which includes the following three levels: Level 1: physical health, good development and nutrition, and normal organ function; Level 2: Except for surgical diseases, there are mild comorbidities and functional compensation is sound; Level 3: Severe coexisting conditions, limited physical activity, but still able to cope with daily activities; 5.Voluntarily participate in this clinical study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria need to be excluded from this study: 1. Patients who have undergone digestive tract surgeries >= 2 times; 2. Patients with liver cirrhosis and active autoimmune diseases; 3. Combined acute infection; 4. Individuals who are allergic to lactulose, have a history of lactulose intolerance, or are deemed unsuitable for lactulose by the attending physician. 5. Individuals with a history of cognitive impairment, severe mental illness, or postoperative complications such as poor cognitive function recovery or delirium; 6. Patients who are currently participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
Small intestinal bacterial overgrowth;

Secondary

MeasureTime frame
Gastrointestinal quality of life index;

Countries

China

Contacts

Public ContactHuang Jianwei

Putuo People’s Hospital, School of Medicine, Tongji University

huangjianwei1124@live.cn+86 139 1664 7091

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026