Digestive tract diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age is 18 years old or above, with no gender restrictions; 2.Patients admitted to the General Surgery Department of Putuo People’s Hospital, School of Medicine, Tongji University and transferred to the general ward after completing digestive surgery for various diseases; 3.Including open surgery and laparoscopic surgery; 4.Having a standard classification III or better physical condition established by the American Society of Anesthesiologists, which includes the following three levels: Level 1: physical health, good development and nutrition, and normal organ function; Level 2: Except for surgical diseases, there are mild comorbidities and functional compensation is sound; Level 3: Severe coexisting conditions, limited physical activity, but still able to cope with daily activities; 5.Voluntarily participate in this clinical study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following criteria need to be excluded from this study: 1. Patients who have undergone digestive tract surgeries >= 2 times; 2. Patients with liver cirrhosis and active autoimmune diseases; 3. Combined acute infection; 4. Individuals who are allergic to lactulose, have a history of lactulose intolerance, or are deemed unsuitable for lactulose by the attending physician. 5. Individuals with a history of cognitive impairment, severe mental illness, or postoperative complications such as poor cognitive function recovery or delirium; 6. Patients who are currently participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Small intestinal bacterial overgrowth; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal quality of life index; | — |
Countries
China
Contacts
Putuo People’s Hospital, School of Medicine, Tongji University