Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 18 to 25 years old. 2. Body Mass Index (BMI): BMI >= 28 kg/m². 3. Health Status: No severe cardiovascular, respiratory, neurological, or other major diseases that may affect exercise capacity. 4. Exercise Capacity: Able to safely perform moderate-to-high intensity aerobic and resistance exercise. 5. Informed Consent: Willing and able to provide written informed consent, and willing to complete all assessments and interventions as required by the study. 6. No Recent Participation in Similar Studies: No participation in other weight loss or exercise intervention studies within the past three months.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or Lactation: Women who are pregnant or breastfeeding will not be included due to specific physiological requirements. 2. Severe Musculoskeletal Disorders: Including, but not limited to, severe arthritis, history of fractures, or muscular diseases that may impair exercise capacity or increase exercise risk. 3. Severe Metabolic Disorders: Such as uncontrolled diabetes, hyperthyroidism, or hypothyroidism, which may affect study outcomes. 4. Mental Health Conditions: Severe depression, anxiety, or other psychiatric disorders that may affect study participation or intervention efficacy. 5. Medication Use: Current use of medications that affect body weight, metabolism, or exercise capacity, such as weight-loss drugs, steroids, or antidepressants. 6. Exercise Intolerance or Allergic Reactions: Presence of allergies or adverse physiological responses to certain types of exercise. 7. Non-compliance: Individuals who, during screening, demonstrate inability or unwillingness to comply with study requirements for intervention and assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Composition;Body Circumference Measurements;Skinfold Thickness;Blood Pressure;Musculoskeletal Ultrasound;One-Repetition Maximum;Maximal Oxygen Uptake;Biochemical Blood Indicators (including fasting blood glucose, fasting insulin, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, uric acid, and blood urea nitrogen);Genotyping performed using the Chinese Genotyping Array platform;Whole Genome Sequencing;Metabolite profiling of plasma samples will be performed using liquid chromatography–mass spectrometry (LC-MS).; | — |
Countries
China
Contacts
Beijing Sport University