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Multi-omics Integrated Analysis of Fat Reduction in Young Adults with Obesity

Multi-omics Integrated Analysis of Fat Reduction in Young Adults with Obesity

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108145
Enrollment
Unknown
Registered
2025-08-26
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Combined Resistance and Aerobic Training Group:Resistance Training Protocol Weeks 1–4: Knee push-ups, standard squats, back extension, glute bridge with diagonal arm raise, and abdominal crunches (12
Aerobic Training Group:Aerobic Training Protocol Weeks 1–4: Running on a 400-meter track, 5–6 laps per session. Weeks 4–8: Running on a 400-meter track, 7–8 laps per session.
High-Intensity Interval Training Group:High-Intensity Interval Training Protocol Weeks 1–4: Jumping jacks, clap under thigh jumps, butt kicks, and simulated rope skipping. Weeks 4–8: Jumping jacks, cl

Sponsors

Beijing Sport University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18 to 25 years old. 2. Body Mass Index (BMI): BMI >= 28 kg/m². 3. Health Status: No severe cardiovascular, respiratory, neurological, or other major diseases that may affect exercise capacity. 4. Exercise Capacity: Able to safely perform moderate-to-high intensity aerobic and resistance exercise. 5. Informed Consent: Willing and able to provide written informed consent, and willing to complete all assessments and interventions as required by the study. 6. No Recent Participation in Similar Studies: No participation in other weight loss or exercise intervention studies within the past three months.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or Lactation: Women who are pregnant or breastfeeding will not be included due to specific physiological requirements. 2. Severe Musculoskeletal Disorders: Including, but not limited to, severe arthritis, history of fractures, or muscular diseases that may impair exercise capacity or increase exercise risk. 3. Severe Metabolic Disorders: Such as uncontrolled diabetes, hyperthyroidism, or hypothyroidism, which may affect study outcomes. 4. Mental Health Conditions: Severe depression, anxiety, or other psychiatric disorders that may affect study participation or intervention efficacy. 5. Medication Use: Current use of medications that affect body weight, metabolism, or exercise capacity, such as weight-loss drugs, steroids, or antidepressants. 6. Exercise Intolerance or Allergic Reactions: Presence of allergies or adverse physiological responses to certain types of exercise. 7. Non-compliance: Individuals who, during screening, demonstrate inability or unwillingness to comply with study requirements for intervention and assessment.

Design outcomes

Primary

MeasureTime frame
Body Composition;Body Circumference Measurements;Skinfold Thickness;Blood Pressure;Musculoskeletal Ultrasound;One-Repetition Maximum;Maximal Oxygen Uptake;Biochemical Blood Indicators (including fasting blood glucose, fasting insulin, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, uric acid, and blood urea nitrogen);Genotyping performed using the Chinese Genotyping Array platform;Whole Genome Sequencing;Metabolite profiling of plasma samples will be performed using liquid chromatography–mass spectrometry (LC-MS).;

Countries

China

Contacts

Public ContactYaqi Wang

Beijing Sport University

wangyaqi@bsu.edu.cn+86 176 1084 8839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 17, 2026