Thoracic ossification of the posterior longitudinal ligament
Conditions
Interventions
Ossification group of the posterior longitudinal ligament of the thoracic vertebrae:The observational study had no intervention measures
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: a. Be over 18 years old and under 80 years old b. Patients with manifestations of thoracic spinal cord disease who have been diagnosed with ossification of the posterior longitudinal ligament of the thoracic vertebrae and ossification of the ligamentum flavum of the thoracic vertebrae through physical examination and imaging c. The patient voluntarily participates in the clinical research, signs the informed consent form, and is able to cooperate with the clinical follow-up
Exclusion criteria
Exclusion criteria: a. Subjects who have participated in clinical trials of other drugs or hospital medical devices within the last six months b. Combined with rheumatoid arthritis c. Combined with ankylosing spondylitis d. Combined with diseases such as kidney, thyroid, and parathyroid disorders that affect endocrine or bone metabolism those e. Those with a history of drug use that may affect bone calcium metabolism f. Those with contraindications to MRI examination g. Patients whose overall physical condition cannot tolerate surgery h. Pregnant women or those planning to become pregnant, as well as lactating women i. Those with mental abnormalities and no ability to act independently j. Other circumstances where the doctor determines that one cannot participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contrast-enhanced ultrasound was used to monitor the changes in spinal cord blood flow in the surgical area;Changes in spinal cord blood oxygen;Somatosensory evoked potentials and motor evoked potentials detected by neuroelectrophysiological tests;Mean arterial pressure during the operation;The modified Japanese Association Thoracic Spinal Nerve Function Score; | — |
Countries
China
Contacts
Public ContactSun chuiguo
Peking University Third Hospital
Outcome results
None listed