Bronchiectasis
Conditions
Interventions
Observation group:None
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Aged 0-18 years 2. Radiologically confirmed bronchiectasis per pediatric HRCT criteria: a) BAR >0.8 (bronchial/adjacent artery diameter ratio) b) Structural signs: loss of tapering OR tram-track sign OR subpleural bronchi 3. Active patient at study site (treatment/follow-up) 4. Consent documentation: - =8 years: Participant assent + guardian consent
Exclusion criteria
Exclusion criteria: Subject (child) or legal guardian declines participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Height;Weight;Laboratory tests (blood routine, CRP, liver function, kidney function, coagulation picture, blood gas analysis, etc.);Pulmonary function (for those aged 4 and above who can cooperate) (FEV1, FVC, FEV1/FVC ratio, V25, etc.);HRCT manifestations (such as Reiff score, distribution of affected lung lobes);Pathogen infection or chronic colonization during the stable and acute phases (nasopharyngeal aspiration or BALF microbial culture results);BALF cytology;Immunological assessment (immunoglobulin levels, specific antibody responses, etc.);Bronchoscopic manifestations;Genetic testing results;Basic vital signs (respiration, heart rate, blood pressure, blood oxygen saturation, etc.); | — |
Countries
China
Contacts
Public ContactZang Na
Children's Hospital of Chongqing Medical University
Outcome results
None listed