Skip to content

Research on Precise Molecular Pathology and Clinical Decision-Making Based on mRNA Expression Profiles and Immunohistochemistry

Research on Precise Molecular Pathology and Clinical Decision-Making Based on mRNA Expression Profiles and Immunohistochemistry

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108110
Enrollment
Unknown
Registered
2025-08-25
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Transplantation

Interventions

Gold Standard:Pathological diagnosis
Index test:Multiplex circular probe technology

Sponsors

The First Affiliated Hospital of Xi 'an Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Older than 18 years old and younger than 65 years old. 2. First receiving a kidney transplant. 3. The patient presented with suspected clinical symptoms of rejection and underwent renal biopsy. 4. The quantity and quality of the remaining clinical tissue biopsy samples meet the testing standards. 5. Patients who have signed the informed consent form and are willing to cooperate with the research.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women. 2.Multiple organ transplantation recipients. 3.Patients with contraindications to immunosuppressant and hormone use. 4.Patients with autoimmune diseases, severe cardiopulmonary diseases or active liver disease. 5.Patients with previous malignant tumors (except successfully treated local non-melanocytic skin cancer). 6.The patient has any form of substance abuse, mental illness, or any condition that the researcher believes may interfere with the patient's understanding of the study requirements. 7.Patients who were not available for routine study visits or follow-up or who were followed at an unaccredited laboratory.

Design outcomes

Primary

MeasureTime frame
Nucleic acid;

Countries

China

Contacts

Public ContactDing Xiaoming

The First Affiliated Hospital of Xi 'an Jiaotong University School of Medicine

xmding@xjtu.edu.cn+86 139 9123 8632

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026