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Does Preoperative Oral Care Reduce Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery?

Preoperative Oral Care and Its Impact on Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery Under General Anesthesia: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108089
Enrollment
Unknown
Registered
2025-08-25
Start date
2025-09-10
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Control group (Routine care group):none
Intervention group(preoperative oral care ):Standardized preoperative oral care intervention

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 65 years; 2.American Society of Anesthesiologists (ASA) physical status classification I–III; 3.Scheduled to undergo non-cardiac surgery under general anesthesia; 4.Expected duration of surgery >= 1 hour and postoperative hospital stay >= 2 days; 5.Able to communicate independently and cooperate with the oral care intervention; 6.Voluntarily agree to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with a preoperative diagnosis of cognitive impairment or psychiatric disorders; 2.Patients scheduled to undergo cranial or neurosurgical procedures;Patients with a history of severe oral infection or who have undergone oral surgery; 3.Patients undergoing emergency surgery; 4.Patients who experience major intraoperative complications, such as massive hemorrhage, septic shock, or cardiac arrest.

Design outcomes

Primary

MeasureTime frame
Postoperative Delirium;

Secondary

MeasureTime frame
30-day postoperative mortality;long-term cognitive function;postoperative infection;postoperative length of hospital stay;Numeric Rating Scale (NRS) scores at 24 and 48 hours after surgery;

Countries

China

Contacts

Public ContactFuhai Ji

The First Affiliated Hospital of Soochow University

jifuhai@hotmail.com+86 512 67780055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026