sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. According to the latest Spsis3.0 definition, patients diagnosed with septic shock within = 100 pg/ml; 3.Age between 18 years and 80 years; 4.The patient or the patient's family has a full understanding of the purpose and significance of this trial, voluntarily participates in this clinical trial, and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with compromised immune function: 1. Primary immunodeficiency diseases; 2. Patients who have received solid organ transplantation or bone marrow transplantation; 3. Those who are currently receiving corticosteroid treatment with a daily dose of >= 20 mg prednisone or an equivalent dose of >= 14 days; 4. Patients with malignant tumors undergoing chemotherapy; 5. Patients receiving other immunosuppressive drugs; 3. Patients with coagulation disorders, those with active bleeding, or those with uncontrollable acute major bleeding (within 24 hours); 4.Patients with malignant tumors and/or wasting diseases, those who cannot undergo lesion clearance (such as surgical patients who cannot undergo surgical treatment), or those with a low body weight (< 35 kg); 5.Platelet count lower than 20×10^9/L; 6. Patients who are expected to die within 48 hours; 7. Patients who have participated in or are currently participating in any clinical studies within the past month;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VIS score;interleukin-6;procalcitonin;hemameba;Hypersensitive C-reactive protein;Length of stay in the ICU;The duration of ventilator use;SOFA score; | — |
Countries
China
Contacts
The Affiliated Hospital of Jiangnan University