thoracic ossification of the posterior longitudinal ligament
Conditions
Interventions
thoracic ossification of the posterior longitudinal ligament:None
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Be over 18 years old and under 80 years old 2. Patients with thoracic spinal cord disease manifestations who have been diagnosed with TOPLL through physical examination and imaging studies 3. The patient voluntarily participates in the clinical research, signs the informed consent form, and is able to cooperate with the clinical follow-up
Exclusion criteria
Exclusion criteria: 1. Those who have participated in clinical trials of other drugs or hospital medical devices within the last six months 2. Combined with rheumatoid arthritis 3. Combined with ankylosing spondylitis 4. Combined with diseases such as kidney, thyroid, and parathyroid disorders that affect endocrine or bone metabolism 5. Those with a history of drug use that may affect bone calcium metabolism 6. Those with contraindications to MRI examination 7. Patients whose overall physical condition cannot tolerate surgery 8. Pregnant women or those planning to become pregnant, as well as lactating women 9. Those with mental abnormalities and no ability to act independently 10. Other situations where the doctor determines that one cannot participate in the experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative spinal cord blood flow;Intraoperative spinal cord blood oxygen saturation;thoracic modified Japanese Orthopaedic Association Scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative neuroelectrophysiological monitoring;Duration of the operation;The amount of bleeding during surgery;Surgical blood transfusion volume;EQ5D;SF36; | — |
Countries
China
Contacts
Public ContactSun Chuiguo
Peking University Third Hospital
Outcome results
None listed